Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 2nd International Conference on Neonatology Paris, France.

Day 1 :

  • Neonatology,Perinatology,Neonatal Nutrition

Session Introduction

Dr.Peter Averkiou, MD

Charles E. Schmidt College of Medicine at Florida Atlantic University

Title: Early Clinical Exposure in Medical Education: The Newborn Nursery Clinical Experience

Dr. Peter Averkiou is a pediatrician and an Associate Professor of Pediatrics at the Charles E. Schmidt College of Medicine at Florida Atlantic University. He is the Co-Director of the four Foundations of Medicine Courses, the Director of the Service Learning Projects, the Director of the Newborn Nursery Clinical Rotation and the Director of the Synthesis and Transition Course at the medical school.



The Newborn Nursery Clinical Experience is an innovative, early exposure for medical students to the hospital setting and family medicine. Early in their second year, our medical students are immersed into the Newborn Nursery, while also experiencing the neonatal intensive care unit (NICU) and attending obstetrical deliveries. They witness, first hand, the interprofessional and interdisciplinary workings of pediatricians, obstetricians, neonatologists, anesthesiologists, nurses and other professionals. The medical students are also instructed on how to read a medical chart and on proper medical documentation and its importance. They also interact with the mother of the patient, as well as other family members that are in attendance, and long-term continuity of integrated care and the focus on the personal patient/patient’s guardian(s) - physician relationship is stressed. This experience is always well-received and highly evaluated by our medical students. It also helps to prepare them for their third-year clinical rotations in family medicine, pediatrics and Ob/Gyn.



Marfel Coleen P. Vergara is a pediatrician from National Children’s Hospital, Philippines. She received a bachelor’s degree in cell and molecular biology from University of the Philippines, and finished Doctor of Medicine program at St. Luke’s Medical Center College of Medicine in Metro Manila, Philippines. She is currently in the Department of Health, serving a local hospital to help the needs and improve the health and wellbeing of the poor Filipino children.


RATIONALE: Invasive candidiasis is a serious condition that occur more commonly in vulnerable populations, such as in preterm neonates especially those in intensive care units. Antifungal prophylaxis has been suggested to decrease mortality in this vulnerable population, with fluconazole as the drug of choice because of its ability to treat more than 90% of Candida species isolates. OBJECTIVE: To determine the efficacy and safety of fluconazole in preventing invasive candidiasis in preterm infants. METHODOLOGY: Publications were searched through PubMed, Cochrane, HERDIN plus, Google Scholar, ResearchGate,, medRxiv, Epistemonikos, WHO International Clinical Trials Registry, and ALIBATA, without language restriction. Randomized controlled trials that compared the effect of prophylactic oral or systemic fluconazole versus placebo in preterm infants, done from January 2000 until present, were included. The methodological quality of the studies were assessed based on the (1) randomization process, (2) deviations from intended interventions, (3) missing outcome data, (4) measurement of the outcome, and (5) selection of the reported result, and a metaanalysis was conducted using STATA. RESULTS: A total of 5 studies were included, with a total of 1084 preterm infants. Prophylactic fluconazole significantly reduced the incidence of invasive candidiasis by 60% (RR=0.40; 95% CI: 0.21, 0.77; p=0.006). The incidence of mortality (RR=0.84; 95% CI: 0.6, 1.2; p=0.324) and necrotizing enterocolitis (RR=0.94; 95% CI: 0.61, 1.44; p=0.770) did not increase among infants give fluconazole prophylaxis as compared to placebo. Fluconazole prophylaxis resulted to a higher mean length of hospital stay versus placebo (SMD=0.16; 95% CI: 0.02, 0.30; p=0.022). Decrease in the incidence of IC also did not depend on the age at first dosage, whether given at 72nd or 120th hour of life (p=0.047, p=0.035), or the dosage used, whether given at 3mg/kg or 6mg/kg (p=0.0043, p=0.0002). CONCLUSION: The use of prophylactic fluconazole decrease invasive fungal infection in preterm infants. While there is no noted increase in mortality and adverse effects, larger clinical trials with longer follow-up periods are still recommended to comprehensively assess the safety profile of fluconazole prophylaxis among preterm infants.


Dr.Niko Miguel Pasatiempo underwent Pediatrics residency training in a government hospital in The Philippines wherein majority of pediatric patients are indigenous. He is passionate in taking care of well and sick children in hospital setting and mostly in community setting. Currently, he is deployed in a remote rural area of his country, providing medical service to the underserved and disadvantaged children, with regard to their health and welfare services.



Neonatal mortality is a global burden and a significant number of neonatal deaths are attributed to early onset sepsis. Prolonged rupture of membranes is an important risk factor for the development of early onset neonatal sepsis (EONS).

This is a prospective cohort study which aimed to identify the incidence of early onset neonatal sepsis following prolonged rupture of membranes among patients admitted at the NICU of Jose R. Reyes Memorial Medical Center.

Results: Out of 105 neonates with maternal history of prolonged rupture of membranes of > 18hours in this study, incidence of neonatal sepsis was reported at 39% with a total of 41 neonates; 3 of them or 7.31% had culture proven sepsis. 64 neonates did not develop clinical signs consistent with sepsis. Majority of neonates in this study were born to term (>37 weeks) pregnancy at 89%, male sex outnumbered females with ratio 2:1, the birth weight of neonates is more than 2500g at 59%, majority were appropriate for gestational age at 83%. Most neonates were delivered via normal spontaneous delivery at 71%. With regards to WBC count, 77.14% belongs to the bracket of 9,000 – 20,000 WBC count with mean WBC count of 15,839. In Neutrophil Count, 61.90% had less than 60,000 with mean neutrophil count of 53,978. In Platelet Count, majority had more than or = 150,000 with 93.33%. Bacterial isolates found in one patient, Staphylococcus epidermidis and two patients with growth of Enterobacter cloace.

Conclusion: Prolonged rupture of membranes was found out to be significantly associated among mothers with history of maternal fever. Also, low birth weight (< 2500g) neonates was found out to be significantly associated with development of sepsis among newborns with prolonged rupture of membranes. Elevated WBC and elevated neutrophil counts were found out to be significant characteristics of neonates with sepsis.